Choose your experience
Seeing lower prices elsewhere? Read the fine print.
Some at-home ketamine programs advertise prices under $150 a month. They usually prescribe a fraction of the dose, often around 15mg a day, with no nasal spray, app-only check-ins instead of a live doctor, and support only in business hours. Pluto plans include up to 30 physician-directed doses a month at 50 to 250mg, your choice of nasal spray, ODT, or troche, a real consultation with a licensed doctor, and unlimited care team messaging. No consult fees, no membership fees, no first-month teaser pricing. Compare the medication you actually get, not just the sticker.
What Ketamine Therapy Helps With
Anxiety
Depression
PTSD
Chronic Stress
Burnout
Low Motivation
What Is Low-Dose Ketamine Therapy?
Not the heavy, sedated clinic kind. Low functional doses that ease stress, anxiety, burnout, and PTSD while you stay clear and get on with your day.
Day Journey With Ketamine
Relief Today. Momentum for Life.
Pluto isn't just ketamine. Start here to calm anxiety and break the habits that hold you back, then stack in weight loss or longevity when you're ready.
Root-cause care, not symptom-chasing.
A clear mind now. A stronger you for life.
Backed by Science. Built for Now.
It delivers rapid relief for anxiety, depression, and PTSD. All without sedating side effects.


Semaglutide / B6 ODT
Ketamine + weight loss
Weight-loss meds help you see results quick.
Together, they rewire both body and mind.
The Complete Protocol
Mind, body, and everything in between.Why PlutoCare?
Got Questions? We've Got Real Answers
PlutoCare’s low-dose ketamine therapy is an evidence-based, needle-free, functional approach to treating treatment-resistant anxiety, depression, PTSD, stress, addiction and dependence and certain chronic pain conditions.
Unlike many ketamine treatments, PlutoCare's functional approach uses low doses so you can stay alert, clear-headed, and productive. Our goal is to fit therapy into your schedule. No large doses that require isolation, therapist-led sessions, or stopping your day.
Whether you're a busy professional, parent, frontline worker, or executive, our low-dose protocol lets you manage PTSD, stress, and anxiety on your terms. In short, our treatments adapt to your life rather than forcing you to pause it.
Your treatment will be either nasal spray or sublingual lozenges / ODT's calibrated for low-dose protocols. Meaning you can use when and where you need. You do not need to be at home or in a clinic to receive treatment. If there are certain safety guidelines they will be directed by your prescribing doctor and communicated with your treatment.
Yes! Ketamine has been approved by the FDA in 1970 for anesthesia. Over the past 50+ years, it has been administered to millions of patients worldwide with a well-characterized safety record.
Researchers first published case reports and trials in 2000 demonstrating rapid antidepressant effects in treatment-resistant depression (TRD) patients, and subsequent studies throughout the 2000s expanded its off-label use for depression, PTSD, and other disorders. Ketamine has been FDA-approved as an anesthetic since 1970. In 2019, the FDA approved esketamine (a ketamine derivative) for treatment-resistant depression.
PlutoCare prescribers may use ketamine off-label when clinically appropriate. Hundreds of thousands of patients have undergone off-label ketamine treatment worldwide over the past two decades.
Our providers will review all potential risks, contraindications, and safety measures with you during your virtual consultation.
Our providers will review all potential risks, contraindications, and safety measures with you during your virtual consultation.
- Major Depressive Disorder (treatment-resistant)
- PTSD and Complex Trauma
- Generalized and Social Anxiety Disorders
- Select Chronic Pain Syndromes (off-label)
- Alcoholism and Dependency Disorders
Users report more joy and optimism combined with the ability to reject or turn-off spiraling thought patterns.
The typical protocol is 2–5 low-dose sessions per day. However your provider will recommend a personalized dosing schedule for you during your consultation.
During your consultation your doctor will tell you what to expect, look out for and explain reasons to reach back to them.
If your treatment is well received you can follow your provider's instructions for safe at-home low-dose use.
If you experience a medical emergency contact 911 before contacting your provider within the patient portal.
Yes all our treatments are designed to work together and in most cases combining treatments can boost efficacy.
Ketamine can be safely combined with weight-loss, sexual health and longevity treatments when approved by your PlutoCare provider.









